Original Article

Six-Month Outcomes of Endoscopic Intragastric Balloon Therapy: A Prospective Single-Center Study

Volume 36 · Issue 11 Publish Date: May 20, 2025
Mahmut Yüksel ORCID Kerem Kenarlı ORCID Fırathan Sarıaltın ORCID Emine Sena Sözen ORCID Ahmet Akbay ORCID Erdoğan Deniz ORCID Kübra Köken ORCID Çağdaş Erdoğan ORCID Mevlüt Hamamcı ORCID Hasan Tankut Köseoğlu ORCID
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Published In

Turkish Journal of Gastroenterology

Volume 36 · Issue 11

Pages: 770-775

History

Published Online: May 20, 2025

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2025 Mahmut Yüksel, Kerem Kenarlı, Fırathan Sarıaltın, Emine Sena Sözen, Ahmet Akbay, Erdoğan Deniz, Kübra Köken, Çağdaş Erdoğan, Mevlüt Hamamcı, Hasan Tankut Köseoğlu

Mahmut Yüksel ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Kerem Kenarlı ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Fırathan Sarıaltın ORCID
Department of Radiology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Emine Sena Sözen ORCID
Department of Internal Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Ahmet Akbay ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Erdoğan Deniz ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Kübra Köken ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Çağdaş Erdoğan ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Mevlüt Hamamcı ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Hasan Tankut Köseoğlu ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Yüksel, M., Kenarlı, K., Sarıaltın, F., Sözen, E. S., Akbay, A., Deniz, E., … Köseoğlu, H. T. (2025). Six-Month Outcomes of Endoscopic Intragastric Balloon Therapy: A Prospective Single-Center Study. Turkish Journal of Gastroenterology, 36(11), 770–775. https://doi.org/10.5152/tjg.2025.25043
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Abstract

Background/Aims: Obesity is a growing global health challenge associated with increased morbidity and mortality. Intragastric balloon therapy has emerged as a minimally invasive alternative for weight management in patients unsuitable for bariatric surgery or as a bridging intervention. This study evaluates the efficacy, safety, and metabolic impacts of intragastric balloon therapy in a prospective cohort.

Materials and Methods: A total of 65 patients underwent endoscopic intragastric balloon therapy between October 2023 and January 2025. Comprehensive baseline evaluations included body weight, body mass index, and computed tomography analysis of visceral and subcutaneous fat tissue thickness. Patients were followed up at 2 and 6 months post procedure. Statistical analysis was performed to assess weight loss, metabolic changes, and safety outcomes.

Results: Of the initial cohort, 62 patients (mean age: 37.89 years; 75.4% female) completed the study. The median body weight decreased significantly from 104.5 kg pre procedure to 88 kg at 6 months (P < .001). Body mass index values similarly declined, with a mean reduction from 37.59 to 32.79 kg/m2 (P < .001). Significant decreases in subcutaneous and visceral fat tissue thickness were observed (P < .001 and P = .032, respectively). Only 1 patient (1.5%) required early balloon removal due to nausea, with no other major complications reported.

Conclusion: Intragastric balloon therapy is an effective and safe intervention for short term weight loss, with significant reductions in adipose tissue. Further research is needed to evaluate its long-term efficacy and metabolic benefits.

 

Cite this article as: Yüksel M, Kenarlı K, Sarıaltın F, et al. Six-month outcomes of endoscopic intragastric balloon therapy: A prospective single-center study. Turk J Gastroenterol. 2025;36(11):770-775.

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 36 · Issue 11
Pages 770-775
DOI 10.5152/tjg.2025.25043
History
Published Online May 20, 2025
License
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright
Copyright (c) 2025 Mahmut Yüksel, Kerem Kenarlı, Fırathan Sarıaltın, Emine Sena Sözen, Ahmet Akbay, Erdoğan Deniz, Kübra Köken, Çağdaş Erdoğan, Mevlüt Hamamcı, Hasan Tankut Köseoğlu
Affiliations
Mahmut Yüksel ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Kerem Kenarlı ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Fırathan Sarıaltın ORCID
Department of Radiology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Emine Sena Sözen ORCID
Department of Internal Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Ahmet Akbay ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Erdoğan Deniz ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Kübra Köken ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Çağdaş Erdoğan ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Mevlüt Hamamcı ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Hasan Tankut Köseoğlu ORCID
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye
Cite this Article
Yüksel, M., Kenarlı, K., Sarıaltın, F., Sözen, E. S., Akbay, A., Deniz, E., … Köseoğlu, H. T. (2025). Six-Month Outcomes of Endoscopic Intragastric Balloon Therapy: A Prospective Single-Center Study. Turkish Journal of Gastroenterology, 36(11), 770–775. https://doi.org/10.5152/tjg.2025.25043
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