Gastrointestinal Endoscopy - Original Article

Can a 1-day clear liquid diet with a split -dose polyethylene glycol overcome conventional practice patterns during the preparation for screening colonoscopy?

Volume 30 · Issue 9 Publish Date: September 15, 2019
Diğdem Özer Etik Nuretdin Suna Cemre Gündüz Ahmet Bostan Alperen Özdemir Bade Yağmur Gürel Ezgi Yenişekerci Ahmet Sedat Boyacıoğlu
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Turkish Journal of Gastroenterology

Volume 30 · Issue 9

Pages: 817-825

History

Published Online: September 15, 2019

Copyright © 2019 Diğdem Özer Etik, Nuretdin Suna, Cemre Gündüz, Ahmet Bostan, Alperen Özdemir, Bade Yağmur Gürel, Ezgi Yenişekerci, Ahmet Sedat Boyacıoğlu

Diğdem Özer Etik
Department of Gastroenterology, Yüksek İhtisas Teaching and Research Hospital, Ankara
Nuretdin Suna
Department of Gastroenterology, Başkent University School of Medicine, Ankara, Turkey
Cemre Gündüz
Department of Internal Disease, Başkent University School of Medicine, Ankara, Turkey
Ahmet Bostan
-Başkent University School of Medicine, Ankara, Turkey
Alperen Özdemir
Başkent University School of Medicine, Ankara, Turkey
Bade Yağmur Gürel
-Başkent University School of Medicine, Ankara, Turkey
Ezgi Yenişekerci
-Başkent University School of Medicine, Ankara, Turkey
Ahmet Sedat Boyacıoğlu
Department of Gastroenterology, Başkent University School of Medicine, Ankara, Turkey
Özer Etik, D., Suna, N., Gündüz, C., Bostan, A., Özdemir, A., Gürel, B. Y., … Boyacıoğlu, A. S. (2019). Can a 1-day clear liquid diet with a split -dose polyethylene glycol overcome conventional practice patterns during the preparation for screening colonoscopy?. Turkish Journal of Gastroenterology, 30(9), 817–825. https://doi.org/10.5152/tjg.2019.19071
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Abstract

Background/Aims: A successful screening colonoscopy is closely linked to the quality of a bowel preparation. In this study, we aimed to determine the impact of a 1-day clear liquid diet (CLD) compared to a 3-day combined diet (CMD) accompanied by a split-dose regimen of polyethylene glycol and electrolyte lavage solution (PEG-ELS) for screening colonoscopy. Materials and Methods: This was a prospective, randomized, endoscopist-blinded study. Patients referred for screening colonoscopy were randomized to four groups as a 1-day CLD+PEG-ELS vs. a 1-day CLD+sulfate free (SF)-PEG-ELS and a 3-day CMD+PEG-ELS vs. a 3-day CMD+SF-PEG-ELS. An assessment of the quality of colon cleaning, tolerability to the preparation, and symptoms related to the preparation were recorded. Results: A total of 506 patients were enrolled in this study. The quality of bowel preparation was significantly inferior in the CMD+PEG-ELS group than CLD+PEG-ELS (p=0.004) and CMD+SF-PEG-ELS groups (p=0.007). There were no statistical differences among the groups in terms of the polyp detection rate. With respect to an easy rating of diet following and the consumption of laxative, there were no significant differences among the four groups. Gastric fullness and nausea/vomiting were pointed out much more, especially in the SF-PEG-ELS users (p=0.008 and p=0.004, respectively). Conclusion: A 1-day CLD was not inferior to a 3-day CMD for colonoscopy preparation in terms of bowel cleaning, the polyp detection rate, and patient tolerance.

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 30 · Issue 9
Pages 817-825
DOI 10.5152/tjg.2019.19071
History
Published Online September 15, 2019
Copyright
Copyright (c) 2019 Diğdem Özer Etik, Nuretdin Suna, Cemre Gündüz, Ahmet Bostan, Alperen Özdemir, Bade Yağmur Gürel, Ezgi Yenişekerci, Ahmet Sedat Boyacıoğlu
Affiliations
Diğdem Özer Etik
Department of Gastroenterology, Yüksek İhtisas Teaching and Research Hospital, Ankara
Nuretdin Suna
Department of Gastroenterology, Başkent University School of Medicine, Ankara, Turkey
Cemre Gündüz
Department of Internal Disease, Başkent University School of Medicine, Ankara, Turkey
Ahmet Bostan
-Başkent University School of Medicine, Ankara, Turkey
Alperen Özdemir
Başkent University School of Medicine, Ankara, Turkey
Bade Yağmur Gürel
-Başkent University School of Medicine, Ankara, Turkey
Ezgi Yenişekerci
-Başkent University School of Medicine, Ankara, Turkey
Ahmet Sedat Boyacıoğlu
Department of Gastroenterology, Başkent University School of Medicine, Ankara, Turkey
Cite this Article
Özer Etik, D., Suna, N., Gündüz, C., Bostan, A., Özdemir, A., Gürel, B. Y., … Boyacıoğlu, A. S. (2019). Can a 1-day clear liquid diet with a split -dose polyethylene glycol overcome conventional practice patterns during the preparation for screening colonoscopy?. Turkish Journal of Gastroenterology, 30(9), 817–825. https://doi.org/10.5152/tjg.2019.19071
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