Turkish Journal of Gastroenterology

Treatment of reflux disease during pregnancy and lactation


Department of Gastroenterology, Başkent University School of Medicine, Ankara, Turkey


Clinic of Gastroenterology, Türkiye Yüksek İhtisas Training and Research Hospital, Ankara, Turkey

Turk J Gastroenterol 2017; 28: Supplement S53-S56
DOI: 10.5152/tjg.2017.14
Keywords : Reflux, pregnancy, safety
Read: 539 Downloads: 197 Published: 25 July 2019


Gastroesophageal reflux disease (GERD) is frequently seen during pregnancy. In the medical treatment of pregnant women with GERD, alginic acid and sucralfate can be used. Calcium- and magnesium-based antacids can also be used, particularly for patients with preeclampsia. In particular, ranitidine -a histamine-2 receptor blocker- is preferred. In the case of non-responsiveness to the abovementioned treatments, proton pump inhibitors (PPIs), except omeprazole, can be given considering the benefit-harm ratio for the mother and fetus after the first trimester. In cases with GERD during the lactation period, drugs having minimum systemic absorption, such as sucralfate and alginic acid, are preferable but there is no data.


 Cite this article as: Dağlı Ü, Kalkan İH. Treatment of reflux disease during pregnancy and lactation. Turk J Gastroenterol 2017;28(Suppl 1); S53-S56



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