Turkish Journal of Gastroenterology
Pancreatobiliary - Original Article

Solid pseudopapillary neoplasms of the pancreas: Case series with a review of the literature


Department of General Surgery, Ege University School of Medicine, İzmir, Turkey


Department of General Surgery, University of Health Sciences Tepecik Training and Research Hospital, İzmir, Turkey


Department of General Surgery, Izmir University of Economics School of Medicine


Department of Gastroeneterology, Ege University School of Medicine, İzmir, Turkey


Department of Pathology, Ege University School of Medicine, İzmir, Turkey

Turk J Gastroenterol 2020; 31: 930-935
DOI: 10.5152/tjg.2020.19227
Read: 1627 Downloads: 775 Published: 01 May 2020

Background/Aims: The solid pseudopapillary neoplasms are quite rare tumors of the pancreas, comprising roughly 1-2% of all pancreatic neoplasms. It has a low malignant potential and usually affects young females. Despite increasing number of articles in the last decade, there is still debate on the pathogenesis, malignant potential and optimal surgical strategy for the solid pseudopapillary neoplasms. 

Materials and Methods: Medical recordings of 326 patients who were operated due to pancreatic mass were retrospectively analyzed. Patient demographics, presenting symptoms, surgical and pathologic characteristics of the tumor, postsurgical course, long-term survival, and other relevant data were extracted from patients’ charts.

Results: Majority of the patients were female in consistency with the classic data in the literature. All the patients underwent curative intent resections. Tumors were commonly localized in the tail of the pancreas making distal pancreatectomy the most commonly performed surgical procedure. Mean tumor diameter was 5.8 centimeters with tumor sizes ranging from 1 to 19 cm.

Conclusion: The solid pseudopapillary neoplasms of the pancreas is a rare tumor with low malignant potential, which is more common in females of reproductive age, with abdominal pain being their most common presentation. The short-term outcomes in patients following surgical R0 resection are excellent. However, proximal placement of the tumor and female gender may have slightly worse prognosis. We hope that our findings from a series of patients represent a contribution to the existing literature on SPN, and authors declare their willingness to provide further details for future meta-analyses.

Cite this article as: Uğuz A, Ünalp ÖV, Akpınar G, et al. Solid pseudopapillary neoplasms of the pancreas: Case series with a review of the literatüre. Turk J Gastroenterol 2020; 31(12): 930-5.

EISSN 2148-5607