Original Article

Efficacy and Safety of Peroral Endoscopic Myotomy in the Treatment of Zenker’s Diverticulum: A Single-Center Experience

Volume 35 · Issue 2 Publish Date: February 15, 2024
Abdullah Murat Buyruk Çağdaş Erdoğan
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Turkish Journal of Gastroenterology

Volume 35 · Issue 2

Pages: 119-124

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Published Online: February 15, 2024

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2024 Abdullah Murat Buyruk, Çağdaş Erdoğan

Abdullah Murat Buyruk
Ege University, Medical faculty, Department of Internal Medicine, Division of Gastroenterology
Çağdaş Erdoğan
Department of Gastroenterology, Ankara City Hospital, Ankara, Turkey
Buyruk, A. M., & Erdoğan, Çağdaş. (2024). Efficacy and Safety of Peroral Endoscopic Myotomy in the Treatment of Zenker’s Diverticulum: A Single-Center Experience. Turkish Journal of Gastroenterology, 35(2), 119–124. https://doi.org/10.5152/tjg.2024.23402
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Abstract

Background/Aims: The efficacy and safety of Zenker’s peroral endoscopic myotomy (Z-POEM), a current method in the treatment of Zenker’s diverticulum (ZD), have been demonstrated in a limited number of studies and case reports. This study aimed to report our experience with the Z-POEM method. Materials and Methods: Patients with ZD who were treated with Z-POEM between January 2019 and March 2023 and had a followup period of at least 3 months were included in the study. Our primary endpoint was clinical success. A Kothari–Haber score (KHS) of 2 or less at 1 month postoperatively was defined as clinical success. Our secondary endpoints were adverse events and recurrence rates. Results: In total, 20 patients (males, 65%; mean age, 63 ± 14.4 years) were treated with Z-POEM. The mean ZD septum length was 33.7 (±11.04) mm. The technical success rate was 100% (20/20), and the clinical success rate was 95% (19/20). In 1 case with a large ZD (septum length of 60 mm), the mucosal septum, which was thought to cause partial persistence of symptoms, was treated by endoscopic septotomy. The mean KHS decreased significantly after Z-POEM (preoperative KHS: 7.3 and postoperative KHS: 0.15, P < .0001). The median follow-up period was 10 months (interquartile range, 3-39). No recurrence was observed in any case. Intraprocedural mild subcutaneous emphysema was observed in 4 (20%) cases. Emphysema regressed spontaneously in the postoperative period without any treatment. Conclusion: Zenker’s peroral endoscopic myotomy is a successful and reliable method in the treatment of ZD, with low recurrence rates. Cite this article as: Buyruk AM, Erdoğan Ç. Efficacy and safety of peroral endoscopic myotomy in the treatment of Zenker’s diverticulum: A single-center experience. Turk J Gastroenterol. 2024;35(2):119-124.

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 35 · Issue 2
Pages 119-124
DOI 10.5152/tjg.2024.23402
History
Published Online February 15, 2024
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Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright
Copyright (c) 2024 Abdullah Murat Buyruk, Çağdaş Erdoğan
Affiliations
Abdullah Murat Buyruk
Ege University, Medical faculty, Department of Internal Medicine, Division of Gastroenterology
Çağdaş Erdoğan
Department of Gastroenterology, Ankara City Hospital, Ankara, Turkey
Cite this Article
Buyruk, A. M., & Erdoğan, Çağdaş. (2024). Efficacy and Safety of Peroral Endoscopic Myotomy in the Treatment of Zenker’s Diverticulum: A Single-Center Experience. Turkish Journal of Gastroenterology, 35(2), 119–124. https://doi.org/10.5152/tjg.2024.23402
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