Turkish Journal of Gastroenterology
Gastrointestinal Tract - Original Article

Fall of another myth for colon cancer: Duration of symptoms does not differ between right- or left-sided colon cancers

1.

Department of General Surgery, Uludağ University School of Medicine, Bursa, Turkey

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Ankara University School of Medicine, Department of General Surgery, Ankara, Turkey

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Department of Biostatistics, Ankara University School of Medicine, Ankara, Turkey

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Department of General Surgery, Dokuz Eylül University School of Medicine, İzmir, Turkey

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Department of General Surgery, İstanbul University İstanbul School of Medicine, İstanbul, Turkey

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Department of General Surgery, Osmangazi University School of Medicine, Eskişehir, Turkey

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Department of General Surgery, Ege University School of Medicine, İzmir, Turkey

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Department of General Surgery, GATA School of Medicine, Ankara, Turkey

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Department of General Surgery, Atatürk University School of Medicine, Erzurum, Turkey

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Department of General Surgery, Cumhuriyet University School of Medicine, Sivas, Turkey

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Department of General Surgery, Dicle University School of Medicine, Diyarbakır, Turkey

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Department of General Surgery, İstanbul University-Cerrahpaşa School of Medicine, İstanbul, Turkey

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Department of General Surgery, Demetevler Oncology Hospital, Ankara, Turkey

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Department of General Surgery, Marmara University School of Medicine, İstanbul, Turkey

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Department of General Surgery, Hacettepe University School of Medicine, Ankara, Turkey

Turk J Gastroenterol 2019; 30: 686-694
DOI: 10.5152/tjg.2019.17770
Read: 492 Downloads: 109 Published: 09 August 2019

Background/Aims: Patients with colorectal cancer continue to present with relatively advanced tumors that are associated with poor oncological outcomes. The aim of the present study was to assess the association between localization, symptom duration, and tumor stage.

Materials and Methods: A prospective, multicenter cohort study was conducted on patients newly diagnosed with a histologically proven colorectal adenocarcinoma. Standardized questionnaire-interviews were performed. Data were collected on principal presenting symptoms, duration of symptoms (time to first presentation to a doctor and time to diagnosis) and treatment, diagnostic procedures, tumor site, and stage of the tumor (tumor, node, and metastasis (TNM)).

Results: A total of 1795 patients with colorectal cancer were interviewed (mean age: 60.76±13.50 years, male patients: 1057, patients aged >50 years: 1444, colon/rectal cancer: 899/850, right side/left side: 383/1250, stage 0-1-2/stage 3-4: 746/923). No statistically significant correlations were found between duration of symptoms and either tumor site or stage. Principal presenting symptoms were significantly associated with left colon cancer. Patients who had “anemia,” “change in bowel habits,” “anal pruritus or discharge,” “weight loss,” and “tumor in right colon” had a significantly longer symptom time.

Conclusion: Symptom duration is not associated with localization, nor is the tumor stage. Diagnosis of colorectal cancer at an earlier stage may be best achieved by screening of the population.

Cite this article as: Öztürk M, Kuzu MA, Öztuna D, et al. Fall of another myth for colon cancer: Duration of symptoms does not differ between right- or left-sided colon cancers. Turk J Gastroenterol 2019; 30(8): 686-94.

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