Turkish Journal of Gastroenterology
Review

Current approach to early gastrointestinal and liver complications of hematopoietic stem cell transplantation

1.

Department of Hematology, Ankara University School of Medicine, Cebeci Hospital, Ankara, Turkey

2.

Department of Gastroenterology, Ankara University School of Medicine, Cebeci Hospital, Ankara, Turkey

Turk J Gastroenterol 2019; 30: 122-131
DOI: 10.5152/tjg.2018.18156
Read: 1101 Downloads: 238 Published: 25 July 2019

Abstract

 

The gastrointestinal (GI) system is one of the most commonly affected sites during a hematopoietic stem cell transplantation (HSCT) due to toxicities of preparative regimens, the accompanying immunodeficiency, and organ damage caused by graft versus host disease. In this review, we focus on early GI and liver complications following autologous (auto-) and allogeneic (allo-) HSCT and clarify both the risk factors and therapeutic strategies. Early GI and liver complications associated with HSCT remain challenging issues. Despite the improvements in this field during the last decade, treatments for these complications still place a significant burden on both patients and the physicians treating these patients. GI and liver complications remain some of the causes of mortality associated with HSCT. For practicing hematologists, oncologists, and gastroenterologists in this field, the awareness and early diagnosis of the GI complications remain important factors to obtain optimal outcomes in this patient population.

 

 

Cite this article as: Atilla E, Ataca Atilla P, Cengiz Seval G, Bektaş M, Demirer T. Current approach to early gastrointestinal and liver complications of hematopoietic stem cell transplantation. Turk J Gastroenterol 2019; 30(2): 122-31.

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