Adverse factors responsible for below-normal platelet count after laparoscopic splenectomy and azygoportal disconnection

Background/Aims: Splenectomy is regarded as an effective curative treatment for thrombocytopenia caused by hypersplenism in patients with cirrhosis. However, in clinical practice, thrombocytopenia is not resolved by splenectomy in all patients. This study aimed to evaluate the adverse factors responsible for platelet (PLT) counts below the normal lower limit following laparoscopic splenectomy and azygoportal disconnection (LSD). Materials and Methods: We retrospectively evaluated the outcomes of 123 cirrhotic patients with portal hypertensive bleeding and secondary hypersplenism, who underwent LSD and who had PLT counts Results: Sixteen patients (13.01%) had PLT counts 50 years and longitudinal spleen diameter ≤160 mm were threshold values for an increased risk of the PLT count Conclusion: Age was an independent positive predictor and longitudinal spleen diameter an independent negative predictor of PLT count Cite this article as: Bai DS, Shao WY, Zhang C, Chen P, Jin SJ, Jiang GQ. Adverse factors responsible for below-normal platelet count after laparoscopic splenectomy and azygoportal disconnection. Turk J Gastroenterol 2019; 30(3): 254-9.