Review

Current approach to early gastrointestinal and liver complications of hematopoietic stem cell transplantation

Volume 30 · Issue 2 Publish Date: July 25, 2019
Erden Atilla Pınar Ataca Atilla Güldane Cengiz Seval Mehmet Bektaş Taner Demirer
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Turkish Journal of Gastroenterology

Volume 30 · Issue 2

Pages: 122-131

History

Published Online: July 25, 2019

Copyright © 2019 Erden Atilla, Pınar Ataca Atilla, Güldane Cengiz Seval, Mehmet Bektaş, Taner Demirer

Erden Atilla
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Pınar Ataca Atilla
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Güldane Cengiz Seval
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Mehmet Bektaş
Department of Gastroenterology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Taner Demirer
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Atilla, E., Ataca Atilla, P., Cengiz Seval, G., Bektaş, M., & Demirer, T. (2019). Current approach to early gastrointestinal and liver complications of hematopoietic stem cell transplantation. Turkish Journal of Gastroenterology, 30(2), 122–131. https://doi.org/10.5152/tjg.2018.18156
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Abstract

The gastrointestinal (GI) system is one of the most commonly affected sites during a hematopoietic stem cell transplantation (HSCT) due to toxicities of preparative regimens, the accompanying immunodeficiency, and organ damage caused by graft versus host disease. In this review, we focus on early GI and liver complications following autologous (auto-) and allogeneic (allo-) HSCT and clarify both the risk factors and therapeutic strategies. Early GI and liver complications associated with HSCT remain challenging issues. Despite the improvements in this field during the last decade, treatments for these complications still place a significant burden on both patients and the physicians treating these patients. GI and liver complications remain some of the causes of mortality associated with HSCT. For practicing hematologists, oncologists, and gastroenterologists in this field, the awareness and early diagnosis of the GI complications remain important factors to obtain optimal outcomes in this patient population. Cite this article as: Atilla E, Ataca Atilla P, Cengiz Seval G, Bektaş M, Demirer T. Current approach to early gastrointestinal and liver complications of hematopoietic stem cell transplantation. Turk J Gastroenterol 2019; 30(2): 122-31.

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 30 · Issue 2
Pages 122-131
DOI 10.5152/tjg.2018.18156
History
Published Online July 25, 2019
Copyright
Copyright (c) 2019 Erden Atilla, Pınar Ataca Atilla, Güldane Cengiz Seval, Mehmet Bektaş, Taner Demirer
Affiliations
Erden Atilla
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Pınar Ataca Atilla
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Güldane Cengiz Seval
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Mehmet Bektaş
Department of Gastroenterology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Taner Demirer
Department of Hematology Ankara University School of Medicine Cebeci Hospital Ankara Turkey
Cite this Article
Atilla, E., Ataca Atilla, P., Cengiz Seval, G., Bektaş, M., & Demirer, T. (2019). Current approach to early gastrointestinal and liver complications of hematopoietic stem cell transplantation. Turkish Journal of Gastroenterology, 30(2), 122–131. https://doi.org/10.5152/tjg.2018.18156
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