Posters

Thyroid manifestations in autoimmune liver diseases: a single center experience

Volume 30 · Issue Supplement 1 Publish Date: July 25, 2019
Celal Ulasoglu Gonca Tamer Nilufer Tekin Kenan Ozendi Ebubekir Senates Ilyas Tuncer
Full Text PDF
DOI

Published In

Turkish Journal of Gastroenterology

Volume 30 · Issue Supplement 1

Pages: 89-90

History

Published Online: July 25, 2019

Copyright © 2019 Celal Ulasoglu, Gonca Tamer, Nilufer Tekin, Kenan Ozendi, Ebubekir Senates, Ilyas Tuncer

Celal Ulasoglu
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Gonca Tamer
Department of Endocrinlogy Goztepe ERH Medeniyet University Istanbul Turkey
Nilufer Tekin
Department of Radiology Goztepe ERH Medeniyet University Istanbul Turkey
Kenan Ozendi
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Ebubekir Senates
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Ilyas Tuncer
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Ulasoglu, C., Tamer, G., Tekin, N., Ozendi, K., Senates, E., & Tuncer, I. (2019). Thyroid manifestations in autoimmune liver diseases: a single center experience. Turkish Journal of Gastroenterology, 30(Supplement 1), 89–90. https://doi.org/10.5152/tjg.2019.59
Endnote/Zotero/Mendeley (RIS) BibTeX
Full Text PDF

Abstract

INTRODUCTION: Thyroid diseases may be seen in various autoimmune and viral liver diseases related to autoimmunity, complications, drugs and other treatment modalities. Revised International Autoimmune Hepatitis Group score adds 2 points for accompanying thyroiditis or another autoimmune disease presence (1,2,3). In this study we aimed to assess the thyroid findings in autoimmune liver diseases (AILD) patients including Autoimmune Hepatitis (AIH), Primary Biliary Cholangitis (PBC), Overlap Syndromes and Primary Sclerosing Cholangitis (PSC). We aimed to assess the thyroid pathologies in our AILD cohort. METHODS: Patients with AILD under follow-up in gastroenterology department of a tertiary hospital (Istanbul Medeniyet University, Goztepe Education and Research Hospital, Istanbul,Turkey) were investigated with palpation, thyroid function tests, autoantibodies and thyroid ultrasonography. The demographic and laboratory data were statistically analysed.  RESULTS: The total registered patients in a single center with AILD were 111 (101 female and 10 male; 55 PBC, 44 AIH, 10 Overlap and 2 PSC) fulfilling relevant criteria for their diagnosis. The mean age of the patients was 56,4±13,6 (23-84). Of these,13 patients had died previously related to liver problems. Of these 98 patients,Hashimoto thyroiditis (21.4%), Hypothyroidia (10%) and Basedow-Graves disease (3.0%) were assessed (Table 1). Thyroid ultrasonography revealed 74.3% had heterogenous parenchyma and 28% had thyroid nodüle(s). One patient had papillary carcinoma which later treated appropriately. Nineteen patients (19.4%) were receiving L-thyroxin.  CONCLUSION: In our AILD patients, thyroid findings were primarily Hashimoto’s thyroiditis and heterogenous parenchyma. Incidentally a thyroid papillary carcinoma was detected and treated appropriately. There was no difference between subgroups by means of thyroiditis and parenchymal heterogenity. Treatment response and clinical severity were not related with thyroid manifestations. Intermittent controls of thyroid gland in AILD patients may be crucial to detect thyroid pathologies before advanced disease.

Most read articles by the same author(s)

1 2 3 > >> 
Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 30 · Issue Supplement 1
Pages 89-90
DOI 10.5152/tjg.2019.59
History
Published Online July 25, 2019
Copyright
Copyright (c) 2019 Celal Ulasoglu, Gonca Tamer, Nilufer Tekin, Kenan Ozendi, Ebubekir Senates, Ilyas Tuncer
Affiliations
Celal Ulasoglu
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Gonca Tamer
Department of Endocrinlogy Goztepe ERH Medeniyet University Istanbul Turkey
Nilufer Tekin
Department of Radiology Goztepe ERH Medeniyet University Istanbul Turkey
Kenan Ozendi
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Ebubekir Senates
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Ilyas Tuncer
Department of Gastroenterology Goztepe ERH Medeniyet University Istanbul Turkey
Cite this Article
Ulasoglu, C., Tamer, G., Tekin, N., Ozendi, K., Senates, E., & Tuncer, I. (2019). Thyroid manifestations in autoimmune liver diseases: a single center experience. Turkish Journal of Gastroenterology, 30(Supplement 1), 89–90. https://doi.org/10.5152/tjg.2019.59
Download Citation
Endnote/Zotero/Mendeley (RIS) BibTeX
Outlines