Published In
Turkish Journal of Gastroenterology
Volume 37 · Issue 2
Pages: 233-241
History
Published Online: October 20, 2025
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright © 2025 Ahmet Tarhan, Yasemin Gökden, Sinem Aydemir, Suzan Önol, Fatma Zülal Özek
Ahmet Tarhan
Department of Internal Medicine, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Yasemin Gökden
Department of Gastroenterology, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Sinem Aydemir
Department of Radiology, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Suzan Önol
Department of Radiology, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Fatma Zülal Özek
Department of Internal Medicine, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Tarhan, A., Gökden, Y., Aydemir, S., Önol, S., & Özek, F. Z. (2025). Evaluation of Pancreatic Steatosis in Patients with Celiac Disease. Turkish Journal of Gastroenterology, 37(2), 233–241. https://doi.org/10.5152/tjg.2025.25069
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Abstract
Background/Aims: Celiac disease, a chronic autoimmune disorder, has been reported to be associated with pancreatic involvement, including exocrine pancreatic insufficiency, pancreatitis, and cystic fibrosis. The aim of this cross-sectional study was to determine the frequency of pancreatic steatosis (PS) in patients with celiac disease and compare it with that in healthy controls.
Materials and Methods: Sixty patients with celiac disease and 60 healthy participants were included in this study. Biochemical and hematological parameters were collected from all participants. Hepatic steatosis (HS) and PS were diagnosed by ultrasonography and were compared between the groups.
Results: Age, gender, and body mass index were similar between the groups (P > .05). Pancreatic steatosis (81.7%) and HS (66.7%) were more prevalent in the celiac group compared to healthy controls (P < .001). A positive and significant correlation was found between PS and HS in the celiac group (rho = 0.464, P < .05). Hepatic steatosis and PS did not differ between tissue transglutaminase Immunoglobulin A (IgA)-positive and -negative patients with celiac disease (P > .05). No differences in HS or PS were found between celiac patients who adhered to a gluten-free diet and those who did not (P > .05).
Conclusion: Celiac disease may be associated with an increased risk of HS and PS.
Cite this article as: Tarhan A, Gökden Y, Aydemir S, Önol S, Özek FZ. Evaluation of pancreatic steatosis in patients with celiac disease. Turk J Gastroenterol. 2026;37(2):233-241.
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Article Info
Published In
Journal
Turkish Journal of Gastroenterology
Volume / Issue
Volume 37 · Issue 2
Pages
233-241
History
Published Online
October 20, 2025
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright
Copyright (c) 2025 Ahmet Tarhan, Yasemin Gökden, Sinem Aydemir, Suzan Önol, Fatma Zülal Özek
Affiliations
Ahmet Tarhan
Department of Internal Medicine, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Yasemin Gökden
Department of Gastroenterology, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Sinem Aydemir
Department of Radiology, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Suzan Önol
Department of Radiology, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Fatma Zülal Özek
Department of Internal Medicine, Health Sciences University Prof.Dr. Cemil Taşcıoğlu City Hospital, İstanbul, Türkiye
Cite this Article
Tarhan, A., Gökden, Y., Aydemir, S., Önol, S., & Özek, F. Z. (2025). Evaluation of Pancreatic Steatosis in Patients with Celiac Disease. Turkish Journal of Gastroenterology, 37(2), 233–241. https://doi.org/10.5152/tjg.2025.25069
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