Optimizing the Personalized Care for the Management of Rectal Cancer: A Consensus Statement

Erman Aytaç; Leyla Özer; Bilgi Baca; Emre Balık; Yersu Kapran; Orhun Cığ Taşkın; Başak Oyan Uluç; Mehmet Ufuk Abacıoğlu; Murat Gönenç; Yasemin Bölükbaşı; Barbaros E. Çil; Bülent Baran; Cem Aygün; Mehmet Erdem Yıldız; Kemal Ünal; Burçak Erkol; Tunç Yaltı; Uğur Özbek; Tan Attila; Nurdan Tözün; Bengi Gürses; Sibel Erdamar; Özlem Er; Nuran Beşe; Orhan Bilge; Güralp Onur Ceyhan; Nil Molinas Mandel; Uğur Selek; Cengiz Yakıcıer; Hülya Kayserili Karabey; Murat Saruç; Volkan Özben; Eren Esen; Emre Özoran; Erkan Vardareli; Levent Güner; İsmail Hamzaoğlu; Dursun Buğra; Tayfun Karahasanoğlu; The İstanbul Group

doi:10.5152/tjg.2022.211103

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Optimizing the Personalized Care for the Management of Rectal Cancer: A Consensus Statement

Volume 33 · Issue 8 Publish Date: August 15, 2022

Erman Aytaç Leyla Özer Bilgi Baca Emre Balık Yersu Kapran Orhun Cığ Taşkın Başak Oyan Uluç Mehmet Ufuk Abacıoğlu Murat Gönenç Yasemin Bölükbaşı Barbaros E. Çil Bülent Baran Cem Aygün Mehmet Erdem Yıldız Kemal Ünal Burçak Erkol Tunç Yaltı Uğur Özbek Tan Attila Nurdan Tözün Bengi Gürses Sibel Erdamar Özlem Er Nuran Beşe Orhan Bilge Güralp Onur Ceyhan Nil Molinas Mandel Uğur Selek Cengiz Yakıcıer Hülya Kayserili Karabey Murat Saruç Volkan Özben Eren Esen Emre Özoran Erkan Vardareli Levent Güner İsmail Hamzaoğlu Dursun Buğra Tayfun Karahasanoğlu The İstanbul Group

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Turkish Journal of Gastroenterology

Volume 33 · Issue 8

Pages: 627-663

History

Published Online: August 15, 2022

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2022 Erman Aytaç, Leyla Özer, Bilgi Baca, Emre Balık, Yersu Kapran, Orhun Cığ Taşkın, Başak Oyan Uluç, Mehmet Ufuk Abacıoğlu, Murat Gönenç, Yasemin Bölükbaşı, Barbaros E. Çil, Bülent Baran, Cem Aygün, Mehmet Erdem Yıldız, Kemal Ünal, Burçak Erkol, Tunç Yaltı, Uğur Özbek, Tan Attila, Nurdan Tözün, Bengi Gürses, Sibel Erdamar, Özlem Er, Nuran Beşe, Orhan Bilge, Güralp Onur Ceyhan, Nil Molinas Mandel, Uğur Selek, Cengiz Yakıcıer, Hülya Kayserili Karabey, Murat Saruç, Volkan Özben, Eren Esen, Emre Özoran, Erkan Vardareli, Levent Güner, İsmail Hamzaoğlu, Dursun Buğra, Tayfun Karahasanoğlu, The İstanbul Group

Erman Aytaç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Leyla Özer

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Bilgi Baca

Department of General Surgery, İstanbul University Cerrahpaşa Medical School, Istanbul

Emre Balık

Department of General Surgery, İstanbul University, İstanbul Medical Faculty, İstanbul

Yersu Kapran

Departments of Pathology, İstanbul University, School of Medicine, İstanbul

Orhun Cığ Taşkın

Koç University Faculty of Medicine, İstanbul, Turkey

Başak Oyan Uluç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Mehmet Ufuk Abacıoğlu

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Murat Gönenç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Yasemin Bölükbaşı

Koç University Faculty of Medicine, İstanbul, Turkey

Barbaros E. Çil

Koç University Faculty of Medicine, İstanbul, Turkey

Bülent Baran

Koç University Faculty of Medicine, İstanbul, Turkey

Cem Aygün

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Mehmet Erdem Yıldız

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Kemal Ünal

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Burçak Erkol

Koç University Faculty of Medicine, İstanbul, Turkey

Tunç Yaltı

Koç University Faculty of Medicine, İstanbul, Turkey

Uğur Özbek

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Tan Attila

Department of Gastroenterology, Koç University School of Medicine, İstanbul, Turkey; Department of Gastroenterology, VKV American Hospital, İstanbul, Turkey

Nurdan Tözün

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Bengi Gürses

Koç University Faculty of Medicine, İstanbul, Turkey

Sibel Erdamar

Departments of Pathology, İstanbul University, Cerrahpasa Medical School, İstanbul

Özlem Er

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Nuran Beşe

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Orhan Bilge

İstanbul Üniversitesi, Hepatopankreatobiliyer Hastalıklar Araştırma ve Uygulama Merkezi

Güralp Onur Ceyhan

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Nil Molinas Mandel

Koç University School of Medicine, İstanbul, Turkey

Uğur Selek

Koç University Faculty of Medicine İstanbul Turkey

Cengiz Yakıcıer

Acıbadem Mehmet Ali Aydınlar University School of Medicine, İstanbul, Turkey

Hülya Kayserili Karabey

Koç University Faculty of Medicine, İstanbul, Turkey

Murat Saruç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Volkan Özben

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Eren Esen

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Emre Özoran

Koç University Faculty of Medicine, İstanbul, Turkey

Erkan Vardareli

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Levent Güner

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

İsmail Hamzaoğlu

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Dursun Buğra

Koç University Faculty of Medicine, İstanbul, Turkey

Tayfun Karahasanoğlu

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

The İstanbul Group

The I?stanbul Group

Aytaç E., Özer L., Baca, B., Balık, E., Kapran, Y., Taşkın O. C., … Group, T. I. (2022). Optimizing the Personalized Care for the Management of Rectal Cancer: A Consensus Statement. Turkish Journal of Gastroenterology, 33(8), 627–663. https://doi.org/10.5152/tjg.2022.211103

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Abstract

Colorectal cancer is the third most common cancer in Turkey. The current guidelines do not provide sufficient information to cover all aspects of the management of rectal cancer. Although treatment has been standardized in terms of the basic principles of neoadjuvant, surgical, and adjuvant therapy, uncertainties in the management of rectal cancer may lead to significant differences in clinical practice. In order to clarify these uncertainties, a consensus program was constructed with the participation of the physicians from the Acıbadem Mehmet Ali Aydınlar and Koç Universities. This program included the physicians from the departments of general surgery, gastroenterology, pathology, radiology, nuclear medicine, medical oncology, radiation oncology, and medical genetics. The gray zones in the management of rectal cancer were determined by reviewing the evidence-based data and current guidelines before the meeting. Topics to be discussed consisted of diagnosis, staging, surgical treatment for the primary disease, use of neoadjuvant and adjuvant treatment, management of recurrent disease, screening, follow-up, and genetic counseling. All those topics were discussed under supervision of a presenter and a chair with active participation of related physicians. The consensus text was structured by centralizing the decisions based on the existing data. Cite this article as: Aytaç E, Özer L, Baca B, et al. Optimizing the personalized care for the management of rectal cancer: A consensus statement. Turk J Gastroenterol. 2022;33(8):627-663.

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Article Info

Published In

Journal Turkish Journal of Gastroenterology

Volume / Issue Volume 33 · Issue 8

Pages 627-663

DOI 10.5152/tjg.2022.211103

History

Published Online August 15, 2022

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright

Copyright (c) 2022 Erman Aytaç, Leyla Özer, Bilgi Baca, Emre Balık, Yersu Kapran, Orhun Cığ Taşkın, Başak Oyan Uluç, Mehmet Ufuk Abacıoğlu, Murat Gönenç, Yasemin Bölükbaşı, Barbaros E. Çil, Bülent Baran, Cem Aygün, Mehmet Erdem Yıldız, Kemal Ünal, Burçak Erkol, Tunç Yaltı, Uğur Özbek, Tan Attila, Nurdan Tözün, Bengi Gürses, Sibel Erdamar, Özlem Er, Nuran Beşe, Orhan Bilge, Güralp Onur Ceyhan, Nil Molinas Mandel, Uğur Selek, Cengiz Yakıcıer, Hülya Kayserili Karabey, Murat Saruç, Volkan Özben, Eren Esen, Emre Özoran, Erkan Vardareli, Levent Güner, İsmail Hamzaoğlu, Dursun Buğra, Tayfun Karahasanoğlu, The İstanbul Group

Affiliations

Erman Aytaç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Leyla Özer

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Bilgi Baca

Department of General Surgery, İstanbul University Cerrahpaşa Medical School, Istanbul

Emre Balık

Department of General Surgery, İstanbul University, İstanbul Medical Faculty, İstanbul

Yersu Kapran

Departments of Pathology, İstanbul University, School of Medicine, İstanbul

Orhun Cığ Taşkın

Koç University Faculty of Medicine, İstanbul, Turkey

Başak Oyan Uluç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Mehmet Ufuk Abacıoğlu

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Murat Gönenç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Yasemin Bölükbaşı

Koç University Faculty of Medicine, İstanbul, Turkey

Barbaros E. Çil

Koç University Faculty of Medicine, İstanbul, Turkey

Bülent Baran

Koç University Faculty of Medicine, İstanbul, Turkey

Cem Aygün

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Mehmet Erdem Yıldız

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Kemal Ünal

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Burçak Erkol

Koç University Faculty of Medicine, İstanbul, Turkey

Tunç Yaltı

Koç University Faculty of Medicine, İstanbul, Turkey

Uğur Özbek

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Tan Attila

Department of Gastroenterology, Koç University School of Medicine, İstanbul, Turkey; Department of Gastroenterology, VKV American Hospital, İstanbul, Turkey

Nurdan Tözün

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Bengi Gürses

Koç University Faculty of Medicine, İstanbul, Turkey

Sibel Erdamar

Departments of Pathology, İstanbul University, Cerrahpasa Medical School, İstanbul

Özlem Er

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Nuran Beşe

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Orhan Bilge

İstanbul Üniversitesi, Hepatopankreatobiliyer Hastalıklar Araştırma ve Uygulama Merkezi

Güralp Onur Ceyhan

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Nil Molinas Mandel

Koç University School of Medicine, İstanbul, Turkey

Uğur Selek

Koç University Faculty of Medicine İstanbul Turkey

Cengiz Yakıcıer

Acıbadem Mehmet Ali Aydınlar University School of Medicine, İstanbul, Turkey

Hülya Kayserili Karabey

Koç University Faculty of Medicine, İstanbul, Turkey

Murat Saruç

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Volkan Özben

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Eren Esen

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Emre Özoran

Koç University Faculty of Medicine, İstanbul, Turkey

Erkan Vardareli

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Levent Güner

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

İsmail Hamzaoğlu

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

Dursun Buğra

Koç University Faculty of Medicine, İstanbul, Turkey

Tayfun Karahasanoğlu

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Turkey

The İstanbul Group

The I?stanbul Group

Cite this Article

Aytaç E., Özer L., Baca, B., Balık, E., Kapran, Y., Taşkın O. C., … Group, T. I. (2022). Optimizing the Personalized Care for the Management of Rectal Cancer: A Consensus Statement. Turkish Journal of Gastroenterology, 33(8), 627–663. https://doi.org/10.5152/tjg.2022.211103

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