Published In
Turkish Journal of Gastroenterology
Volume 32 · Issue 3
Pages: 302-312
History
Published Online: March 15, 2021
Copyright © 2021 Bülent Değertekin, Nurdan Tozun, Figen Demir, Gizem Söylemez, Şirin Parkan, Ezgi Gürtay, Deniz Mutlu, Meltem Toraman, Tolga Hayrettin Seymenoğlu
Bülent Değertekin
Department of Gastroenterology and Radiology, Ufuk University School of Medicine, Ankara
Nurdan Tozun
Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey
Figen Demir
Division of Social Health, Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Gizem Söylemez
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Şirin Parkan
Check-up Unit of Acibadem Kadikoy Hospital, Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Ezgi Gürtay
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Deniz Mutlu
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Meltem Toraman
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Tolga Hayrettin Seymenoğlu
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Değertekin, B., Tozun, N., Demir, F., Söylemez, G., Parkan, Şirin, Gürtay, E., … Seymenoğlu, T. H. (2021). The Changing Prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) in Turkey in the Last Decade. Turkish Journal of Gastroenterology, 32(3), 302–312. https://doi.org/10.5152/tjg.2021.20062
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Abstract
Background/Aims: The true prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) is unknown in Turkey due to a lack of population-based studies. The aim of this study was (i) to determine the overall and region-specific prevalence of NAFLD in Turkey; (ii) to analyze the factors associated with the prevalence; and (iii) to determine the nationwide change in the prevalence of NAFLD in the last decade.
Materials and methods: The 10-year data (2007 to 2016) of 113,239 apparently healthy subjects visiting the check-up clinics of Acibadem Hospitals Group were retrospectively analyzed. A subgroup of patients (n=8120) statistically representing the bigger cohort were selected. The prevalence was analyzed according to ultrasound findings, age, sex, body mass index (BMI), geographical region, and time periods trisected as 2007-2010, 2011-2013 and 2014-2016.
Results: The overall prevalence of NAFLD in Turkey was found to be 48.3%. It was highest among people >50 years of age (65.6%), male sex (64.0%), with a BMI>25 kg/m2 (63.5%) and in Central and Eastern Anatolia regions (57.1% and 55.7%, respectively). The prevalence of NAFLD was 43.5% between 2007-2010, 47.6% between 2011-2013 and 53.1% between 2014-2016 and the rate of increase was 22%. Multivariate analysis showed that male sex, serum alanine aminotransferase (ALT) level, older age, BMI, type-II diabetes mellitus, hypertension and dyslipidemia were independent factors associated with NAFLD.
Conclusion: NAFLD is a highly prevalent disease affecting almost half of the Turkish population (48.3%). We are faced with a dramatic increase in NAFLD prevalence in the past 10 years.
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Article Info
Published In
Journal
Turkish Journal of Gastroenterology
Volume / Issue
Volume 32 · Issue 3
Pages
302-312
History
Published Online
March 15, 2021
Copyright
Copyright (c) 2021 Bülent Değertekin, Nurdan Tozun, Figen Demir, Gizem Söylemez, Şirin Parkan, Ezgi Gürtay, Deniz Mutlu, Meltem Toraman, Tolga Hayrettin Seymenoğlu
Affiliations
Bülent Değertekin
Department of Gastroenterology and Radiology, Ufuk University School of Medicine, Ankara
Nurdan Tozun
Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey
Figen Demir
Division of Social Health, Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Gizem Söylemez
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Şirin Parkan
Check-up Unit of Acibadem Kadikoy Hospital, Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Ezgi Gürtay
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Deniz Mutlu
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Meltem Toraman
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Tolga Hayrettin Seymenoğlu
Acibadem Mehmet Ali Aydinlar University School of Medicine, İstanbul, Turkey
Cite this Article
Değertekin, B., Tozun, N., Demir, F., Söylemez, G., Parkan, Şirin, Gürtay, E., … Seymenoğlu, T. H. (2021). The Changing Prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) in Turkey in the Last Decade. Turkish Journal of Gastroenterology, 32(3), 302–312. https://doi.org/10.5152/tjg.2021.20062
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