Original Article

Assessment of sleep pattern and quality before and after liver transplantation using different methods

Volume 31 · Issue 8 Publish Date: August 15, 2020
Genco Gençdal Gamze Türker Işıl Yazıcı Gençdal Burçak Ekinci Şencan Acar Ayhan Dinçkan Murat Akyıldız
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Published In

Turkish Journal of Gastroenterology

Volume 31 · Issue 8

Pages: 581-587

History

Published Online: August 15, 2020

Copyright © 2020 Genco Gençdal, Gamze Türker, Işıl Yazıcı Gençdal, Burçak Ekinci, Şencan Acar, Ayhan Dinçkan, Murat Akyıldız

Genco Gençdal
Ataşehir Memorial Hastanesi, Organ nakil Merkezi, Gastroenteroloji Kliniği
Gamze Türker
Yeni Yüzyıl ÜTF GOP Hastanesi, Göğüs Hastalıkları Kliniği
Işıl Yazıcı Gençdal
Bakırköy Dr. Sadi Konuk. EAH Nöroloji Kliniği
Burçak Ekinci
Adatıp İstanbul Hastanesi, Nöroloji Kliniği
Şencan Acar
Ataşehir Memorial Hastanesi, Organ Nakil Merkezi,İç Hastalıkları
Ayhan Dinçkan
Departments of General Surgery, Akdeniz University, School of Medicine, Antalya
Murat Akyıldız
Departments of Gastroenterology, Ege University, School of Medicine, İzmir
Gençdal, G., Türker, G., Yazıcı Gençdal, I., Ekinci, B., Acar, Şencan, Dinçkan, A., & Akyıldız, M. (2020). Assessment of sleep pattern and quality before and after liver transplantation using different methods. Turkish Journal of Gastroenterology, 31(8), 581–587. https://doi.org/10.5152/tjg.2020.18809
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Abstract

Background/Aims: Sleep disorders (SDs) are frequently seen in cirrhotics. Polysomnography (PSG), actigraphy and electroencephalogram (EEG) are common objective methods to diagnose SDs. The most commonly used subjective methods are the Pittsburgh Sleep Quality Index (PSQI) and Epworth sleepiness scale (ESS). In this study, we aimed to evaluate the effect of liver transplantation on SDs by using a combination of objective (PSG and EEG) and subjective methods (PSQI and ESS). Material and Methods: Eighteen cirrhotic patients on a liver transplantation (LTx) waiting list were included in the study. Patient clinical status, biochemical parameters were evaluated. All patients completed validated Turkish forms of the PSQI and ESS before and nine-months after LTx. All patients underwent EEG and PSG before and nine-months after LTx. Results: Eighteen patients with liver cirrhosis (male: 12; 66.7%, mean age: 53.22±10.43 years) were included in the study. Pre-transplant and nine-month post-transplant mean PSQI and ESS scores were 8.4±3.11 and 7.28±3.89; 4.5±2.8 and 4.72±2.91 (p<0.01), respectively. Pre-transplantation, metabolic encephalopathy was detected in 6 of 18 patients by EEG, while metabolic encephalopathy was detected in only one patient post-transplant. Post-transplantation PSG sleep duration (all stages) increased relative to pre-transplant PSG values. Sleep latency (SL) and REM (Rapid eye movement) latency were found to be reduced relative to pre-transplant values. Conclusion: This was a pilot study comparing SDs in pre- and post-liver transplant patients by combining subjective and objective methods. Significant SD improvements were found at the ninth month.

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 31 · Issue 8
Pages 581-587
DOI 10.5152/tjg.2020.18809
History
Published Online August 15, 2020
Copyright
Copyright (c) 2020 Genco Gençdal, Gamze Türker, Işıl Yazıcı Gençdal, Burçak Ekinci, Şencan Acar, Ayhan Dinçkan, Murat Akyıldız
Affiliations
Genco Gençdal
Ataşehir Memorial Hastanesi, Organ nakil Merkezi, Gastroenteroloji Kliniği
Gamze Türker
Yeni Yüzyıl ÜTF GOP Hastanesi, Göğüs Hastalıkları Kliniği
Işıl Yazıcı Gençdal
Bakırköy Dr. Sadi Konuk. EAH Nöroloji Kliniği
Burçak Ekinci
Adatıp İstanbul Hastanesi, Nöroloji Kliniği
Şencan Acar
Ataşehir Memorial Hastanesi, Organ Nakil Merkezi,İç Hastalıkları
Ayhan Dinçkan
Departments of General Surgery, Akdeniz University, School of Medicine, Antalya
Murat Akyıldız
Departments of Gastroenterology, Ege University, School of Medicine, İzmir
Cite this Article
Gençdal, G., Türker, G., Yazıcı Gençdal, I., Ekinci, B., Acar, Şencan, Dinçkan, A., & Akyıldız, M. (2020). Assessment of sleep pattern and quality before and after liver transplantation using different methods. Turkish Journal of Gastroenterology, 31(8), 581–587. https://doi.org/10.5152/tjg.2020.18809
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