Clinical comparative analysis of various duodenal diseases in different age groups
Main Article Content
Abstract
Background/Aims: To investigate differences and relevance of various common duodenal diseases in different parts in the aspects of age, gender, helicobacter pylori (H.pylori) infection, application of non-steroidal anti-inflammatory drugs (NSAIDs), smoking, or drinking.
Materials and Methods: the medical records of various duodenal diseases were collected and tested for difference using the 2 test or Fisher exact probability method.
Results: (1) the proportions of Duodenal ulcer (DU), inflammation, and duodenal bulb diseases in the adult group (A) (47.98%, 36.70%, 66.63%) were higher than the elderly group (E) (41.38%, 29.83%, 56.82%), but the proportions of duodenal diverticulum (DD), tumor, diseases in the descending and ascending segments (2.95%, 1.43%, 9.14%, 0.14%) were lower than Group E (13.73%, 3.69%, 19.41%, 0.76%) (P < 0.001). (2) The positive rate of H.pylori (63.64%) in the duodenal bulb diseases was higher than the bulb-descending segment (53.75%), but the application rate of NSAIDs (16.44%) in the duodenal bulb-descending diseases was lower than the descending segment (24.81%) (P<0.001).
Conclusions: (1) DU, inflammation, and duodenal bulb diseases are common in adults, but DD, tumor, diseases in the descending and ascending segments are more common in the elderly. (2) Compared with duodenal bulb-descending diseases, the application of NSAIDs has greater impact on the diseases in the descending segment, and the rate of H. pylori infection is higher in duodenal bulb diseases.
Materials and Methods: the medical records of various duodenal diseases were collected and tested for difference using the 2 test or Fisher exact probability method.
Results: (1) the proportions of Duodenal ulcer (DU), inflammation, and duodenal bulb diseases in the adult group (A) (47.98%, 36.70%, 66.63%) were higher than the elderly group (E) (41.38%, 29.83%, 56.82%), but the proportions of duodenal diverticulum (DD), tumor, diseases in the descending and ascending segments (2.95%, 1.43%, 9.14%, 0.14%) were lower than Group E (13.73%, 3.69%, 19.41%, 0.76%) (P < 0.001). (2) The positive rate of H.pylori (63.64%) in the duodenal bulb diseases was higher than the bulb-descending segment (53.75%), but the application rate of NSAIDs (16.44%) in the duodenal bulb-descending diseases was lower than the descending segment (24.81%) (P<0.001).
Conclusions: (1) DU, inflammation, and duodenal bulb diseases are common in adults, but DD, tumor, diseases in the descending and ascending segments are more common in the elderly. (2) Compared with duodenal bulb-descending diseases, the application of NSAIDs has greater impact on the diseases in the descending segment, and the rate of H. pylori infection is higher in duodenal bulb diseases.