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Gastroesophageal reflux disease and the relationship with Helicobacter pylori

Volume 28 · Issue 1 Publish Date: January 15, 2017
Zeynel Mungan Binnur Pınarbaşı Şimşek
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Turkish Journal of Gastroenterology

Volume 28 · Issue 1

Pages: S61-S67

History

Published Online: January 15, 2017

Copyright © 2017 Zeynel Mungan, Binnur Pınarbaşı Şimşek

Zeynel Mungan
Department of Gastroenterology, Koç University School of Medicine, İstanbul, Turkey; Department of Gastroenterology, VKV American Hospital, İstanbul, Turkey
Binnur Pınarbaşı Şimşek
Department of Gastroenterology, İstinye University School of Medicine, İstanbul, Turkey
Mungan, Z., & Pınarbaşı Şimşek, B. (2017). Gastroesophageal reflux disease and the relationship with Helicobacter pylori. Turkish Journal of Gastroenterology, 28(1), S61-S67. https://doi.org/10.5152/tjg.2017.16
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Abstract

Abstract After Helicobacter pylori was identified, and its relationship with peptic ulcer disease was exactly shown, the relationship of this bacterium with gastroesophageal reflux disease (GERD) gained momentum and discussions continue to this day. We reviewed the literature for the relationship between H. pylori and GERD. According to the existing data, there is no relationship between GERD and H. pylori presence. Successful eradication therapy does not have an impact on the emergence or exacerbation of GERD. However Barrett's esophagus and esophageal adenocarcinoma are less frequent, especially in the presence of CagA positive H. pylori infections. Long-term use of proton pump inhibitor (PPI) may have an impact on the development of atrophy and/or intestinal metaplasia in H. pylori positive patients; therefore, H. pylori eradication is recommended in patients that should use long-term PPI. As a conclusion, H. pylori screening and the eradication decision should be independent of GERD, except for patients that will use long-term PPI. Cite this article as: Mungan Z, Pınarbaşı Şimşek B. Gastroesophageal reflux disease and the relationship with Helicobacter pylori. Turk J Gastroenterol 2017;28(Suppl 1); S61-S67 Full Text Turkish

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 28 · Issue 1
Pages S61-S67
DOI 10.5152/tjg.2017.16
History
Published Online January 15, 2017
Copyright
Copyright (c) 2017 Zeynel Mungan, Binnur Pınarbaşı Şimşek
Affiliations
Zeynel Mungan
Department of Gastroenterology, Koç University School of Medicine, İstanbul, Turkey; Department of Gastroenterology, VKV American Hospital, İstanbul, Turkey
Binnur Pınarbaşı Şimşek
Department of Gastroenterology, İstinye University School of Medicine, İstanbul, Turkey
Cite this Article
Mungan, Z., & Pınarbaşı Şimşek, B. (2017). Gastroesophageal reflux disease and the relationship with Helicobacter pylori. Turkish Journal of Gastroenterology, 28(1), S61-S67. https://doi.org/10.5152/tjg.2017.16
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