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Abstract
Abstract Although uncommon, acute pancreatitis is a well-recognized, but generally serious, complication following liver transplantation. In addition to being more prevalent in patients who underwent liver transplantation than in the general population, it has a more aggressive course and can be responsible for significant morbidity and mortality. The post-liver transplant population has altered anatomy, increased comorbidities, and requires a myriad of drugs. These characteristics make them different from the pre-transplant population. Despite their retrospective nature, prior studies have identified numerous etiological factors that are associated with an increased risk of acute pancreatitis following liver transplantation. These can be broadly classified into the following four categories: surgical and anatomical factors, infections, post-transplant management, and post-transplant complications.The aim of this systematic review is to assimilate the available information regarding acute pancreatitis following adult liver transplantation to describe the risk factors and natural history of the disease and to highlight possible areas for further investigation.
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Article Info
Published In
Journal
Turkish Journal of Gastroenterology
Volume / Issue
Volume 26 · Issue 6
Pages
450-455
History
Published Online
November 15, 2015
Copyright
Copyright (c) 2015 Ahmet Danalıoğlu, Oscar JL. Mitchell, Vikesh K. Singh, Ahmet Nasuh Danalıoğlu, Hakan Şentürk, Andrew M. Cameron, Ahmet Gürakar
Affiliations
Ahmet Danalıoğlu
Department of Internal Medicine, Division of Gastroenterology, Bezmialem Vakıf University School of Medicine, İstanbul, Turkey
Oscar JL. Mitchell
Department of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
Vikesh K. Singh
Department of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
Ahmet Nasuh Danalıoğlu
Department of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States;Department of Gastroenterology, Bezmialem Vakıf University Faculty of Medicine, İstanbul, Turkey
Hakan Şentürk
Department of Gastroenterology, Bezmialem Vakıf University Faculty of Medicine, İstanbul, Turkey
Andrew M. Cameron
Department of Surgery, Transplant Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
Ahmet Gürakar
Division of Liver Transplantation Medicine/Hepatology, Nazih Zuhdi Transplantation Institute, Integris Baptist Medical Center, Oklahoma City, OK.
Cite this Article
Danalıoğlu, A., JL. Mitchell, O., K. Singh, V., Danalıoğlu, A. N., Şentürk, H., M. Cameron, A., & Gürakar, A. (2015). Acute pancreatitis following adult liver transplantation: A systematic review. Turkish Journal of Gastroenterology, 26(6), 450–455. https://doi.org/10.5152/tjg.2015.0427
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