E-ISSN 2148-5607
Original Article
Assessment of presence and grade of activity in ileal Crohn’s disease
1 Department of Gastroenterology, İzmir Atatürk Teaching and Research Hospital, İzmir, Turkey  
2 Department of Radiology, İzmir Atatürk Teaching and Research Hospital, İzmir, Turkey  
3 Department of Biostatistics, Vanderbilt University, Nashville, USA  
Turk J Gastroenterol 2014; 25: 264-270
DOI: 10.5152/tjg.2014.3862
Key Words: Crohn’s disease, activation, ileocolonoscopy, magnetic resonance enterography

Background/Aims: To assess the sensitivity of magnetic resonance enterography (MRE) in the diagnosis of Crohn’s disease (CD) activity and correlation between endoscopic and MRE scores in predicting the activity grade.


Materials and Methods: Twenty-five ileal CD patients with clinical and biochemical evidence of activation underwent ileocolonoscopy and MRE within 7 days of their application. Simplified endoscopic scoring of CD (SES-CD) and MRE scores was done and compared with each other and other parameters of activation (CRP, leukocyte count, platelet count).


Results: The sensitivity of MRE scoring was found to be 92%; however, the statistical correlation with SES-CD was not significant (p=0.83) for the grading of the activity.


Conclusion: MRE scoring is sensitive enough to use in CD activity evaluation; however, it can not be used alone, and it is rather a complementary technique to endoscopy and is especially valuable for patients with extraluminal disease. 

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