E-ISSN 2148-5607
Original Article
Safety and effectivity of ERCP in pregnant patients; a high-volume study with long-term follow-up
1 Department of Gastroenterology, Gaziantep University School of Medicine, Gaziantep, Turkey  
2 Department of General Surgery, İstanbul Bilim University School of Medicine, İstanbul, Turkey  
Turk J Gastroenterol ; : -
DOI: 10.5152/tjg.2019.18799
Key Words: Pregnancy, endoscopic retrograde cholangiopancreatography, radiation, choledocholithiasis, pancreatitis

Background/Aims: Pancreaticobiliary diseases are observed more frequently in pregnancy due to increased biliary stone formation. There are some concerns about the use of endoscopic retrograde cholangiopancreatography (ERCP) because of potential fetal exposure to radiation and serious adverse events such as post ERCP pancreatitis which increases fetal or maternal morbidity and mortality. The aim of this study is to evaluate the efficacy and safety of ERCP during pregnancy and to present our experience with 25 pregnant patients.


Materials and Methods: This study included 25 pregnant patients who underwent ERCP due to biliopancreatic pathologies between 2010 and 2017. Indications for ERCP were choledocholithiasis (n=12), biliary pancreatitis (n=9) and acute cholangitis (n=4). ERCP procedures were performed using fluoroscopy (n=18) and non-radiation technique (n=7). The duration of fluoroscopy was recorded in all cases. Patients were assessed for fetal and maternal complications.


Results: The mean age of the patients was 29.4 (range, 21-40) years, and the mean duration of pregnancy was 19.9 weeks. All the 25 ERCP procedures were performed successfully. Biliary sphincterotomy was performed in all patients, and 18 patients with choledocholithiasis underwent stone extraction. The average procedure time was 11 min, and the average duration of fluoroscopy was 6 s. There were no major complications in any patient. After the deliveries, the newborns were apparently healthy for a follow-up period of 1-7 years.


Conclusion: Either conventional or non-radiation ERCP procedures can be performed successfully in pregnancy, without increasing the feto-maternal complications when performed by experienced endoscopists.


Cite this article as: Konduk BT, Bayraktar O. Safety and effectivity of ERCP in pregnant patients; a high-volume study with long-term follow-up. Turk J Gastroenterol 2019; DOI: 10.5152/tjg.2019.18799

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