ISSN 1300-4948 | E-ISSN 2148-5607
Case Report
In extremis diagnosis of celiac disease and concomitant wheat allergy
1 Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy  
2 Department of Clinical Medicine, Sapienza University, Rome, Italy  
Turk J Gastroenterol 2018; 29: 515-517
DOI: 10.5152/tjg.2018.17889
Key Words: Celiac disease, wheat allergy, organ culture, histology, gluten-free diet
Abstract

 

Celiac disease (CD) and concomitant wheat allergy are not commonly described in the literature. Both can have almost the same treatment consisting of a gluten-free or wheat-free diet. On the other hand, they are based on totally different pathogenetic mechanisms and can be easily underdiagnosed, particularly CD.

We describe a peculiar case of a young female patient affected by wheat allergy whose serological and histological data were not diagnostic for CD. Organ culture system successfully detected specific antibodies for CD in duodenal biopsy supernatant, supporting the diagnosis of CD.

 

Cite this article as: Borghini R, Donato G, Marino M, Casale R, Di Tola M, Picarelli A. In extremis diagnosis of celiac disease and concomitant wheat allergy. Turk J Gastroenterol 2018; 29: 515-7.

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AVES | Copyright © 2018 Turkish Society of Gastroenterology | Latest Update: 22.10.2018